US Patent Issued to AP Biosciences on May 20 for "PD-L1 and OX40 binding proteins for cancer regulation" (Taiwanese, American Inventors)

ALEXANDRIA, Va., June 16 -- United States Patent no. 12,304,961, issued on May 20, was assigned to AP Biosciences Inc. (Taipei, Taiwan).

"PD-L1 and OX40 binding proteins for cancer regulation" was invented by Jhong-Jhe You (Taipei, Taiwan), Ching-Hsuan Hsu (Taoyuan, Taiwan), Po-Lin Huang (Taipei, Taiwan), Hung-Tsai Kan (New Taipei, Taiwan), Ting-Yi Chang (New Taipei, Taiwan), Hsin-Ta Hsieh (Taipei, Taiwan) and Jeng-Horng Her (San Jose, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided are monospecific and bispecific proteins that bind specifically to OX40 and/or PD-L1. Exemplary proteins release the inhibition through PD-L1 and stimulate T cell through OX40. Exemplary polyvalent proteins compris...