US Patent Issued to Antibiotic Alternatives on Oct. 21 for "Non-transgene transfection for therapeutic purposes" (Minnesota Inventors)

ALEXANDRIA, Va., Oct. 28 -- United States Patent no. 12,448,421, issued on Oct. 21, was assigned to Antibiotic Alternatives LLC (Minneapolis).

"Non-transgene transfection for therapeutic purposes" was invented by Mark C. Herzberg (Minneapolis), Karen Farnie Ross (St. Paul, Minn.) and Brent S. Sorenson (Maplewood, Minn.).

According to the abstract* released by the U.S. Patent & Trademark Office: "This disclosure describes compositions and methods involved in tumor suppression and inhibiting infection of cells by pathogens. Generally, the compositions include an mRNA cargo that can provide a therapeutic benefit after being introduced into an epithelial cell. In some cases, the mRNA can encode a polypeptide. In some cases, the polypeptide ca...