ALEXANDRIA, Va., June 6 -- United States Patent no. 12,280,034, issued on April 22, was assigned to Anavex Life Sciences Corp. (New York).

"Sigma-1 receptor agonist systolic blood pressure therapy" was invented by Christopher U. Missling (New York).

According to the abstract* released by the U.S. Patent & Trademark Office: "A method for lowering systolic blood pressure in a patient exhibiting resistance to a antihypertensive therapy with one or more drugs, the method comprising administering to the patient ANAVEX(R)2-73 at a dose and frequency effective to provide a reduction of at least about 3 mmHg in one or more blood pressure parameters selected from trough sitting systolic, 24-hour ambulatory systolic, and maximum diurnal systolic bl...