ALEXANDRIA, Va., July 30 -- United States Patent no. 12,371,501, issued on July 29, was assigned to AmMax Bio Inc. (Redwood City, Calif.).
"Extended local release of anti-CSFR1 antibodies" was invented by Laman Alani (Menlo Park, Calif.), Chung-Chiang Hsu (Los Altos Hills, Calif.) and Kirk William Johnson (Moraga, Calif.).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides compositions and methods for extended release of certain types of antibodies in vivo. It was discovered that such antibodies are able to initiate reversible gelation of hyaluronic acid (HA) by creating a depot that dissociates over time to release the antibody without any impact on its physical and chemical proper...