US Patent Issued to Amgen on Oct. 7 for "Synthesis of vinylic protected alcohol intermediates" (North Carolina, California Inventors)

ALEXANDRIA, Va., Oct. 8 -- United States Patent no. 12,435,049, issued on Oct. 7, was assigned to Amgen Inc. (Thousand Oaks, Calif.).

"Synthesis of vinylic protected alcohol intermediates" was invented by Austin G. Smith (Cary, N.C.) and Liang Huang (Thousand Oaks, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are processes for synthesizing intermediates useful in preparing Mcl-1 inhibitors. In particular, provided herein are processes for synthesizing compound D, wherein OPG and R1 are described herein. Compound D can be useful in synthesizing compound A1, or a salt of solvate thereof, and compound A2, or a salt of solvate thereof."

The patent was filed on April 27, 2021, under Appl...