ALEXANDRIA, Va., Oct. 8 -- United States Patent no. 12,435,058, issued on Oct. 7, was assigned to Amgen Inc. (Thousand Oaks, Calif.).
"KIF18A inhibitors" was invented by Nuria A. Tamayo (Newbury Park, Calif.), Matthew Richard Kaller (Ventura, Calif.), Thomas T. Nguyen (Newbury Park, Calif.), Nobuko Nishimura (West Hills, Calif.), Qiufen May Xue (Thousand Oaks, Calif.) and John Gordon Allen (Newbury Park, Calif.).
According to the abstract* released by the U.S. Patent & Trademark Office: "Compounds of formula (I): as defined herein, and synthetic intermediates thereof, which are capable of modulating KIF18A protein thereby influencing the process of cell cycle and cell proliferation to treat cancer and cancer-related diseases. The inventio...