ALEXANDRIA, Va., Oct. 21 -- United States Patent no. 12,441,705, issued on Oct. 14, was assigned to Amgen Inc. (Thousand Oaks, Calif.).

"KIF18A inhibitors" was invented by Nuria A Tamayo (Newbury Park, Calif.), Abhisek Banerjee (Karnataka, India), Jian Jeffrey Chen (San Diego), Kexue Li (Newbury, Calif.), Liping H. Pettus (Thousand Oaks, Calif.), Matthew Paul Bourbeau (Woodland Hills, Calif.) and Lei Jia (San Diego).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to chemical compounds having a general formula (I), as defined herein, and synthetic intermediates thereof, which are capable of modulating KIF18A protein thereby influencing the process of cell cycle and cell proliferati...