US Patent Issued to Amgen on March 4 for "Cyclobutyl dihydroquinoline sulfonamide compounds" (Massachusetts Inventors)

ALEXANDRIA, Va., March 5 -- United States Patent no. 12,240,839, issued on March 4, was assigned to Amgen Inc. (Thousand Oaks, Calif.).

"Cyclobutyl dihydroquinoline sulfonamide compounds" was invented by Benjamin C Milgram (Cambridge, Mass.), Isaac E Marx (Arlington, Mass.), Haoxuan Wang (Somerville, Mass.) and Alan H Cherney (Somerville, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides a cyclobutyl dihydroquinoline sulfonamide compound of Formula (I), an enantiomer, diastereoisomer, atropisomer thereof, a mixture thereof, or a pharmaceutically acceptable salt thereof, that inhibits voltage-gated sodium channels, in particular Nav1.7. The compounds are useful for the treatm...