US Patent Issued to Amgen on March 25 for "Excipients to reduce the viscosity of antibody formulations and formulation compositions" (California Inventors)

ALEXANDRIA, Va., March 26 -- United States Patent no. 12,257,343, issued on March 25, was assigned to Amgen Inc. (Thousand Oaks, Calif.).

"Excipients to reduce the viscosity of antibody formulations and formulation compositions" was invented by Jian Hua Gu (Thousand Oaks, Calif.), Robert Matthew Fesinmeyer (Newbury Park, Calif.) and Rulin Qian (Newbury Park, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "This invention concerns a series of excipients capable of effectively reducing the viscosity of protein formulations. The viscosity reducing excipients are oligopeptides (e.g., dipeptides, tripeptides) comprising at least one arginine. The peptides may also include basic or acidic or hydrophilic or hy...