ALEXANDRIA, Va., March 19 -- United States Patent no. 12,251,474, issued on March 18, was assigned to Amgen Inc. (Thousand Oaks, Calif.).
"Process for lyophilized pharmaceutical formulations of a therapeutic protein" was invented by Clea Talley (Camarillo, Calif.).
According to the abstract* released by the U.S. Patent & Trademark Office: "This invention concerns a process for making a lyophilized pharmaceutical formulation of a therapeutic protein, which comprises (a) providing a formulation of a bulk amount of the therapeutic protein, (b) measuring the concentration of the therapeutic protein in said bulk formulation, (c) adjusting the fill weight of the protein in said bulk formulation to achieve a fixed dose of the protein, and (d) ly...