ALEXANDRIA, Va., June 4 -- United States Patent no. 12,318,447, issued on June 3, was assigned to Amgen Inc. (Thousand Oaks, Calif.).

"Lyophilized powder configured for reconstitution as a liquid pharmaceutical formulation with reduced viscosity and method of preparing thereof" was invented by Christopher James Sloey (Newbury Park, Calif.) and Sekhar Kanapuram (Thousand Oaks, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "A method for reducing the viscosity of a pharmaceutical formulation is provided that utilizes a viscosity-reducing concentration of an excipient selected from the group consisting of the n-acetyl arginine, n-acetyl lysine, n-acetyl proline and mixtures thereof in combination with a t...