US Patent Issued to Amgen on Feb. 18 for "Continuous manufacturing process for bispecific antibody products" (California Inventors)

ALEXANDRIA, Va., Feb. 19 -- United States Patent no. 12,227,571, issued on Feb. 18, was assigned to Amgen Inc. (Thousand Oaks, Calif.).

"Continuous manufacturing process for bispecific antibody products" was invented by Chetan Goudar (Newbury Park, Calif.), Rohini Deshpande (Camarillo, Calif.), Natalia Gomez (Playa Vista, Calif.), Hedieh Barkhordarian (Newbury Park, Calif.) and Yan Wang (Thousand Oaks, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides a continuous upstream manufacturing process for the production of bispecific antibody products, which comprise at least two binding domains. The process comprises at least the steps of (i) providing in a perfusion bioreactor a...