ALEXANDRIA, Va., April 9 -- United States Patent no. 12,269,898, issued on April 8, was assigned to Amgen Inc. (Thousand Oaks, Calif.).
"Transthyretin immunoglobulin fusions" was invented by Kenneth Walker (Newbury Park, Calif.).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to transthyretin (TTR) fusions useful in the dimerization and tetramerization of antibodies and antibody fragments, such as Fabs. The TTR fusions proteins described herein are particularly useful in increasing antibody avidity and in enhancing antigen clustering. Methods for treating diseases using the fusion proteins of the present invention are described herein."
The patent was filed on Oct. 3, 2018, under...