US Patent Issued to American Gene Technologies International on Sept. 9 for "Vector system for expressing regulatory RNA" (Maryland Inventors)

ALEXANDRIA, Va., Sept. 10 -- United States Patent no. 12,410,445, issued on Sept. 9, was assigned to American Gene Technologies International Inc. (Rockville, Md.).

"Vector system for expressing regulatory RNA" was invented by Tyler Lahusen (Rockville, Md.), Lingzhi Xiao (Rockville, Md.) and Charles David Pauza (Rockville, Md.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Viral vectors, lentiviral particles, and modified cells are disclosed. They encode or express a small RNA capable of targeting the KIF11 gene. In embodiments, the viral vectors and lentiviral particles further comprise and a KIF11 gene whose non-coding region has been modified such that it is resistant to activity by the small RNA."

The p...