US Patent Issued to Amber Bio on July 8 for "Gene-modifying endonucleases" (California Inventors)

ALEXANDRIA, Va., July 9 -- United States Patent no. 12,351,818, issued on July 8, was assigned to Amber Bio Inc. (San Francisco).

"Gene-modifying endonucleases" was invented by Basem Al-Shayeb (San Francisco), Jacob Borrajo (San Francisco), Mohammad Kamyab Javanmardi (San Francisco) and Kushagra Sharma (San Francisco).

According to the abstract* released by the U.S. Patent & Trademark Office: "The disclosure relates to compositions and methods that modify target nucleic acids, as well as methods of detecting nucleic acids. Various compositions are described herein, including compositions comprising endonucleases, endonuclease systems, and chimeric proteins having the endonuclease and a nucleic-acid modulating domain or a nucleic acid modi...