ALEXANDRIA, Va., March 19 -- United States Patent no. 12,253,468, issued on March 18, was assigned to Altius Institute for Biomedical Sciences (Seattle).

"Methods for fluorescence imaging microscopy and nano-fish" was invented by John A. Stamatoyannopoulos (Seattle), Shreeram Akilesh (Seattle) and Vivek Nandakumar (Seattle).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed herein are methods of detecting a target nucleic acid sequence, determining the localization of the target nucleic acid sequence, and/or quantifying the number of target nucleic acid sequences in a cell. This method may be used on small target nucleic acid sequences, and may be referred to as Nano-FISH."

The patent was filed on May ...