ALEXANDRIA, Va., Nov. 11 -- United States Patent no. 12,466,842, issued on Nov. 11, was assigned to ALTEROME THERAPEUTICS INC. (San Diego).

"Substituted pyrido [4,3-dpyrimidines as KRAS modulators" was invented by Michael David Bartberger (Sherman Oaks, Calif.), Yi Fan (San Diego), Eric Anthony Murphy (San Marcos, Calif.) and Xuefeng Zhu (San Diego).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are inhibitors of KRAS, pharmaceutical compositions comprising the inhibitory compounds, and methods for using the KRAS inhibitory compounds for the treatment of diseases or disorders."

The patent was filed on May 20, 2025, under Application No. 19/213,875.

*For further information, including images,...