US Patent Issued to Alpine Immune Sciences on May 20 for "April and BAFF inhibitory immunomodulatory proteins and methods of use thereof" (Washington, California Inventors)

ALEXANDRIA, Va., June 16 -- United States Patent no. 12,304,943, issued on May 20, was assigned to Alpine Immune Sciences Inc. (Seattle).

"April and BAFF inhibitory immunomodulatory proteins and methods of use thereof" was invented by Stacey Dillon (Seattle), Mark Rixon (Seattle), Lawrence Evans (Seattle, Calif.), Daniel William Demonte (Seattle), Joseph L. Kuijper (Seattle) and Stanford L. Peng (Seattle).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are immunomodulatory proteins that exhibit neutralizing activity of BAFF and APRIL (or BAFF/APRIL heterotrimers). The immunomodulatory proteins provided herein include variant domains of Transmembrane Activator and CAML Interactor (TACI). Among p...