ALEXANDRIA, Va., June 12 -- United States Patent no. 12,297,253, issued on May 13, was assigned to Alpine Immune Sciences Inc. (Seattle).
"Multi-domain immunomodulatory proteins and methods of use thereof" was invented by Ryan Swanson (Seattle).
According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are multi-domain immunomodulatory proteins, nucleic acids encoding such immunomodulatory proteins, cells engineered to express the immunomodulatory proteins and infectious agents containing nucleic acid encoding the immunomodulatory proteins. The immunomodulatory proteins bind both an inhibitory receptor and a receptor involved in activation signaling cascades in an immune cell, such as a T cell. The immuno...