US Patent Issued to Alpine Immune Sciences on July 15 for "CTLA-4 variant immunomodulatory proteins and uses thereof" (Washington Inventors)

ALEXANDRIA, Va., July 16 -- United States Patent no. 12,358,969, issued on July 15, was assigned to Alpine Immune Sciences Inc. (Seattle).

"CTLA-4 variant immunomodulatory proteins and uses thereof" was invented by Lawrence Evans (Seattle), Joseph L. Kuijper (Seattle) and Ryan Swanson (Seattle).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are variant CTLA-4 polypeptides and immunomodulatory proteins and nucleic acids encoding such proteins. The immunomodulatory proteins provide therapeutic utility for a variety of disease applications, including for treatment of autoimmune or inflammatory conditions. Compositions and methods for making and using such proteins are provided."

The patent was f...