ALEXANDRIA, Va., Nov. 25 -- United States Patent no. 12,480,125, issued on Nov. 25, was assigned to Alnylam Pharmaceuticals Inc. (Cambridge, Mass.).

"Patatin-like phospholipase domain containing 3 (PNPLA3) iRNA compositions and methods of use thereof" was invented by Frederic Tremblay (Boston), James D. McIninch (Burlington, Mass.), Adam Castoreno (Framingham, Mass.), Mark K. Schlegel (Boston) and Charalambos Kaittanis (Cambridge, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to RNAi agents, e.g., double stranded RNA (dsRNA) agents, targeting the Patatin-Like Phospholipase Domain Containing 3 (PNPLA3) gene. The invention also relates to methods of using such RNAi agents t...