US Patent Issued to Alnylam Pharmaceuticals on Nov. 11 for "Angiopoietin-like 3 (ANGPTL3) iRNA compositions and methods of use thereof" (Massachusetts Inventors)

ALEXANDRIA, Va., Nov. 11 -- United States Patent no. 12,467,051, issued on Nov. 11, was assigned to Alnylam Pharmaceuticals Inc. (Cambridge, Mass.).

"Angiopoietin-like 3 (ANGPTL3) iRNA compositions and methods of use thereof" was invented by Brian Bettencourt (Groton, Mass.), William Querbes (Boston), Kevin Fitzgerald (Brookline, Mass.), Maria Frank-Kamenetsky (Brookline, Mass.), Stuart Milstein (Arlington, Mass.) and Svetlana Shulga Morskaya (Sudbury, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The invention relates to double-stranded ribonucleic acid (dsRNA) compositions targeting the ANGPTL3 gene, as well as methods of inhibiting expression of ANGPTL3 and methods of treating subjects having a dis...