US Patent Issued to Alnylam Pharmaceuticals on Dec. 9 for "Angiopoietin-like 3 (ANGPTL3) iRNA compositions and methods of use thereof" (Massachusetts Inventors)

ALEXANDRIA, Va., Dec. 9 -- United States Patent no. 12,492,401, issued on Dec. 9, was assigned to Alnylam Pharmaceuticals Inc. (Cambridge, Mass.).

"Angiopoietin-like 3 (ANGPTL3) iRNA compositions and methods of use thereof" was invented by William Querbes (Boston), Kevin Fitzgerald (Brookline, Mass.), James Butler (Lynnfield, Mass.), Stephanie Williams (Littleton, Mass.), Gregory Hinkle (Plymouth, Mass.) and Martin A. Maier (Belmont, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The invention relates to double-stranded ribonucleic acid (dsRNA) compositions targeting the ANGPTL3 gene, as well as methods of inhibiting expression of ANGPTL3 and methods of treating subjects having a disorder of lipid meta...