US Patent Issued to Alnylam Pharmaceuticals on Aug. 12 for "Modified double-stranded RNA agents" (Massachusetts Inventors)

ALEXANDRIA, Va., Aug. 12 -- United States Patent no. 12,385,044, issued on Aug. 12, was assigned to Alnylam Pharmaceuticals Inc. (Cambridge, Mass.).

"Modified double-stranded RNA agents" was invented by Martin Maier (Cambridge, Mass.), Don Foster (Cambridge, Mass.), Stuart Milstein (Cambridge, Mass.), Satya Kuchimanchi (Cambridge, Mass.), Vasant Jadhav (Cambridge, Mass.), Kallanthottathil Rajeev (Cambridge, Mass.), Muthiah Manoharan (Cambridge, Mass.) and Rubina Parmar (Cambridge, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "One aspect of the present invention relates to double-stranded RNA (dsRNA) agent capable of inhibiting the expression of a target gene. The sense strand of the dsRNA agent compri...