ALEXANDRIA, Va., Dec. 9 -- United States Patent no. 12,491,352, issued on Dec. 9, was assigned to Alma Lasers Ltd. (Israel).
"Sonotrode" was invented by Alexander Britva (Migdal Ha'Emek, Israel), Alexander Dverin (Netanya, Israel), Yevgeny Pens (Kiryat Bialik, Israel) and Ziv Karni (Kfar Shmaryahu, Israel).
According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed are a sonotrode and its use for transdermal delivery of therapeutic or cosmetic compounds. The sonotrode 10 comprises a tubular neck 14 attached at a proximal end to a solid head 12 and ending at a distal end in a flared foot 16. When coupled to an ultrasonic transducer and applied to skin of a human or animal, the sonotrode enhances the delivery of c...