ALEXANDRIA, Va., March 19 -- United States Patent no. 12,251,494, issued on March 18, was assigned to AlloSource (Centennial, Colo.).

"Cellular bone grafts, and methods of manufacture and use" was invented by Reginald Stilwell (Parker, Colo.), Ramasamy Sakthivel (Parker, Colo.) and William Maslanik (Littleton, Colo.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The disclosure provides bone graft materials, methods for their use and manufacture. Exemplary bone graft materials comprise combining a radiopaque component with a cancellous bone component to produce a bone graft material, wherein the cancellous bone component comprises native osteoreparative cells. Methods for treating a subject with the bone graf...