US Patent Issued to Allogene Therapeutics on Jan. 20 for "Chimeric cytokine receptors comprising TGF Beta binding domains" (California Inventors)

ALEXANDRIA, Va., Jan. 20 -- United States Patent no. 12,528,856, issued on Jan. 20, was assigned to Allogene Therapeutics Inc. (South San Francisco, Calif.).

"Chimeric cytokine receptors comprising TGF Beta binding domains" was invented by Regina Junhui Lin (San Mateo, Calif.), Siler Panowski (Berkeley, Calif.), Thomas John Van Blarcom (Oakland, Calif.), Shanshan Lang (San Mateo, Calif.) and Barbra Johnson Sasu (San Francisco).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are chimeric cytokine receptors bearing a binding domain capable of binding a TGF-Beta ligand or a TGF-Beta receptor antibody. When present on chimeric antigen receptor (CAR)-bearing immune cells (CAR-T-cells), such receptor...