US Patent Issued to Allegheny Singer Research Institute on Oct. 7 for "Covalent modification and controlled delivery of mu opioid receptor antagonists" (Pennsylvania Inventors)

ALEXANDRIA, Va., Oct. 8 -- United States Patent no. 12,433,883, issued on Oct. 7, was assigned to Allegheny Singer Research Institute (Pittsburgh).

"Covalent modification and controlled delivery of mu opioid receptor antagonists" was invented by Saadyah Averick (Pittsburgh) and Andrew Kassick (Wexford, Pa.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Polymer conjugates comprising a hydrophobic biodegradable polymer covalently attached to a mu opioid receptor (MOR) antagonist are described. Biodegradable covalent nanoparticles comprising the hydrophobic biodegradable polymer covalently attached to a MOR antagonist are provided as a vehicle for the sustained delivery of the MOR antagonist. The described MOR ...