US Patent Issued to Alexion Pharmaceuticals on Dec. 16 for "Monovalent anti-properdin antibodies and antibody fragments" (Connecticut Inventors)

ALEXANDRIA, Va., Dec. 16 -- United States Patent no. 12,497,445, issued on Dec. 16, was assigned to Alexion Pharmaceuticals Inc. (Boston).

"Monovalent anti-properdin antibodies and antibody fragments" was invented by Douglas L. Sheridan (Branford, Conn.), Paul P. Tamburini (Kensington, Conn.), Taneisha Ann-Tanara Mack (East Hampton, Conn.) and Walter C. Voegtli (Killingworth, Conn.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Described herein are isolated monovalent antibodies or antibody fragments thereof that bind human properdin. Such antibodies are useful in methods of treatment for diseases mediated by alternative complement pathway dysregulation."

The patent was filed on Nov. 9, 2021, under Applicat...