US Patent Issued to ALEGRE USA on Nov. 4 for "System for generating immunoglobulin scaffolds for grafting non-human CDR amino acid sequences" (California Inventor)

ALEXANDRIA, Va., Nov. 6 -- United States Patent no. 12,460,018, issued on Nov. 4, was assigned to ALEGRE USA LLC (London).

"System for generating immunoglobulin scaffolds for grafting non-human CDR amino acid sequences" was invented by Jacob Glanville (San Francisco).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to a method for producing a population of nucleic acids encoding at least one protein comprising at least one immunoglobulin variable domain having a non-human-derived CDR3 amino acid sequence embedded in essentially human framework sequences, as well as to a population of nucleic acids and a population of proteins relates thereto and uses thereof."

The patent was filed...