ALEXANDRIA, Va., Sept. 30 -- United States Patent no. 12,428,492, issued on Sept. 30, was assigned to Albert-Ludwigs-Universitaet Freiburg (Freiburg, Germany).

"Chimeric antigen receptors that bind to prostate specific membrane antigen" was invented by Toni Cathomen (Freiburg, Germany), Philipp Wolf (Sexau, Germany), Jamal Alzubi (Freiburg, Germany), Susanne Schultze-Seemann (Merzhausen, Germany) and Irina Kuckuck (Freiburg, Germany).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to a novel chimeric antigen receptor (CAR) comprising an antigen-binding fragment which binds specifically to PSMA antigen, and a method of manufacturing high-quality CAR T cell products by transfection ...