ALEXANDRIA, Va., March 26 -- United States Patent no. 12,258,417, issued on March 25, was assigned to AKAMIS BIO Ltd. (Oxfordshire, Great Britain).
"Adenovirus armed with bispecific T cell engager" was invented by Brian Robert Champion (Abingdon, Great Britain), Alice Claire Noel Bromley (Abingdon, Great Britain), Joshua David Freedman (Chigwell, Great Britain), Kerry David Fisher (Witney, Great Britain) and Leonard William Seymour (Wootton by Woodstock, Great Britain).
According to the abstract* released by the U.S. Patent & Trademark Office: "A modified adenovirus, in particular Enadenotucirev (EnAd), armed with at least two bispecific T cell engagers each comprising at least two binding domains, wherein at least one of the domains is s...