US Patent Issued to AGSINO GENSOURCES on May 13 for "pAPN mutant and composition for site-directed modification of pAPN gene and application thereof" (Chinese Inventors)

ALEXANDRIA, Va., June 12 -- United States Patent no. 12,297,468, issued on May 13, was assigned to AGSINO GENSOURCES Co. LTD. (Shenzhen, China).

"pAPN mutant and composition for site-directed modification of pAPN gene and application thereof" was invented by Kui Li (Shenzhen, China), Yulian Mu (Shenzhen, China) and Lei Huang (Shenzhen, China).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides a pAPN mutant and a composition for site-directed modification of pAPN gene and application thereof, involving the field of gene editing technology. The mutated pAPN mutant with an alanine at position 734 can maintain its normal expression, while reducing the ability of a host expressing the pA...