ALEXANDRIA, Va., Jan. 28 -- United States Patent no. 12,534,492, issued on Jan. 27, was assigned to Agilent Technologies Inc. (Santa Clara, Calif.).
"Methods and kits to improve the fluorescent signal of DMB-labeled sialic acids" was invented by Francis T. Haxo (San Francisco).
According to the abstract* released by the U.S. Patent & Trademark Office: "The invention relates to a method and a kit for stably detecting sialic acid by an enzyme method. The method comprises the following steps of: generating N-acetylneuraminic acid from bound sialic acid under the catalysis of neuraminic acid aldolase; transforming the N-acetylneuraminic acid into N-acetylmannosamine under the catalysis of neuraminidase; reacting the product with mannosamine d...