US Patent Issued to Agenus, Merck Sharp & Dohme on July 1 for "Anti-ILT4 antibodies and antigen-binding fragments" (German, American Inventors)

ALEXANDRIA, Va., July 3 -- United States Patent no. 12,344,670, issued on July 1, was assigned to Agenus Inc. (Lexington, Mass.) and Merck Sharp & Dohme LLC (Rahway, N.J.).

"Anti-ILT4 antibodies and antigen-binding fragments" was invented by Milan Blanusa (Jena, Germany), Barbara Joyce-Shaikh (San Jose, Calif.), Andrea Claudia Schuster (Jena, Germany), Kornelia Schultze (Jena, Germany) and Luis A. Zuniga (Mountain View, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides antibodies and antigen-binding fragments thereof that bind to ILT4 (immunoglobulin-like transcript 4) and combinations thereof, e.g., with an anti-PD1 antibody. Also provided are methods of use thereof, for e...