US Patent Issued to AETAS PHARMA on March 18 for "Method for producing optically active 1, 4-benzothiazepine-1-oxide derivative" (Japanese Inventor)

ALEXANDRIA, Va., March 19 -- United States Patent no. 12,252,483, issued on March 18, was assigned to AETAS PHARMA Co. LTD. (Tokyo).

"Method for producing optically active 1, 4-benzothiazepine-1-oxide derivative" was invented by Sayuri Hirano (Osaka, Japan).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention addresses the problem of providing an efficient asymmetric synthesis method for an optically active 1,4-benzothiazepine-1-oxide derivative.[Solution] According to the present invention, an optically active 1,4-benzothiazepine-1-oxide derivative is efficiently produced by reacting a 1,4-benzothiazepine derivative or a salt thereof with a reagent containing a titanium compound, a chiral dio...