ALEXANDRIA, Va., June 10 -- United States Patent no. 12,290,493, issued on May 6, was assigned to Advanced Respiratory Technologies Inc. (Largo, Fla.).

"More potent and less toxic formulations of epinephrine and methods of medical use" was invented by Darren Rubin (Largo, Fla.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides pharmaceutical formulations of levorotatory-epinephrine, l-epinephrine, more potent and less toxic than existing pharmaceutical formulations of epinephrine, along with methods of producing and using these pharmaceutical formulations of l-epinephrine, including preventing and or treating hypotension and hemostasis under surgical anesthesia."

The patent was fi...