US Patent Issued to Adimab on Jan. 20 for "Rationally designed, synthetic antibody libraries and uses therefor" (New Hampshire Inventors)

ALEXANDRIA, Va., Jan. 20 -- United States Patent no. 12,529,164, issued on Jan. 20, was assigned to Adimab LLC (Lebanon, N.H.).

"Rationally designed, synthetic antibody libraries and uses therefor" was invented by Maximiliano Vasquez (Lebanon, N.H.), Michael Feldhaus (Lebanon, N.H.), Tillman U. Gerngross (Lebanon, N.H.) and K. Dane Wittrup (Lebanon, N.H.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention overcomes the inadequacies inherent in the known methods for generating libraries of antibody-encoding polynucleotides by specifically designing the libraries with directed sequence and length diversity. The libraries are designed to reflect the preimmune repertoire naturally created by the...