US Patent Issued to ADAMA MAKHTESHIM on Nov. 4 for "Preparation of substituted pyrazoles and their use as anthranilamides precursors" (Israeli, Chinese Inventors)

ALEXANDRIA, Va., Nov. 6 -- United States Patent no. 12,459,913, issued on Nov. 4, was assigned to ADAMA MAKHTESHIM LTD. (Beer Sheva, Israel).

"Preparation of substituted pyrazoles and their use as anthranilamides precursors" was invented by Thomas Zell (Beer Sheva, Israel), Jie Li (Nanjing, China), Itsik Bar-Nahum (Kfar-Gibton, Israel) and Avihai Yacovan (Mazkeret Batya, Israel).

According to the abstract* released by the U.S. Patent & Trademark Office: "A method is disclosed for preparing pyrazole derivative 3-bromo-5-methyl-1-H-pyrazole-N-2-chloropyridine (compound of Formula I) by reacting of a compound of Formula II with halogen substituted pyridine optionally in the presence of base and organic solvent or by decarboxylation of pyrazo...