ALEXANDRIA, Va., Aug. 6 -- United States Patent no. 12,378,319, issued on Aug. 5, was assigned to Adagene Inc. (Grand Cayman, Cayman Islands).
"Anti-CD137 molecules and use thereof" was invented by Peter Peizhi Luo (Suzhou, China), Fangyong Du (Suzhou, China), Yan Li (Suzhou, China), Guizhong Liu (Suzhou, China), Jun Chen (Suzhou, China), Xiaohong She (Suzhou, China) and Peter Cheung (Suzhou, China).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides antibodies that bind to human CD137 or antigen binding fragments thereof, nucleic acid encoding the same, therapeutic compositions thereof, and their use to enhance T-cell function to upregulate cell-mediated immune responses and for th...