ALEXANDRIA, Va., Dec. 2 -- United States Patent no. 12,485,119, issued on Dec. 2, was assigned to Actelion Pharmaceuticals Ltd (Allschwil, Switzerland).

"Methods of treating pulmonary arterial hypertension" was invented by Alessandro Maresta (Allschwil, Switzerland) and Loic Perchenet (Allschwil, Switzerland).

According to the abstract* released by the U.S. Patent & Trademark Office: "The disclosure relates to methods of reducing the risk of disease progression in a patient with pulmonary arterial hypertension (PAH), comprising administering to a patient in need thereof, an initial triple combination therapy of an endothelin receptor antagonist (ERA), a phosphodiesterase type 5 (PDE-5) inhibitor, and a prostacyclin receptor agonist (IP re...