US Patent Issued to ACELOT on May 27 for "Substituted piperazines as disrupters of AB42 oligomer formation" (California Inventors)

ALEXANDRIA, Va., June 17 -- United States Patent no. 12,312,296, issued on May 27, was assigned to ACELOT INC. (South San Francisco, Calif.).

"Substituted piperazines as disrupters of AB42 oligomer formation" was invented by Ambuj K. Singh (Santa Barbara, Calif.) and Christian A. Lang (Santa Barbara, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Described herein, inter alia, are certain substituted piperazines, for example, having the Formula 182, and pharmaceutical compositions for the treatment and prevention of diseases related to the formation of ABeta42 oligomers in a subject. It further provides a method of reducing formation of or disrupting ABeta42 oligomers in a subject, the method comprisin...