US Patent Issued to Acceleron Pharma on March 4 for "Variant ActRIIB proteins and uses thereof" (Massachusetts Inventors)

ALEXANDRIA, Va., March 5 -- United States Patent no. 12,240,887, issued on March 4, was assigned to Acceleron Pharma Inc. (Cambridge, Mass.).

"Variant ActRIIB proteins and uses thereof" was invented by Ravindra Kumar (Cambridge, Mass.), Asya Grinberg (Cambridge, Mass.) and Erik M. Vogan (Cambridge, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "In certain aspects, the present invention provides compositions and methods for modulating (promoting or inhibiting) growth of red blood cells or a tissue, such as bone, cartilage, muscle, fat, and/or neuronal tissue. The present invention also provides methods of screening compounds that modulate activity of an ActRIIB protein and/or an ActRIIB ligand. The comp...