US Patent Issued to ACCELERON PHARMA on March 25 for "ALK4:actriib heteromultimers and uses thereof" (Massachusetts Inventors)

ALEXANDRIA, Va., March 26 -- United States Patent no. 12,258,380, issued on March 25, was assigned to ACCELERON PHARMA INC. (Cambridge, Mass.).

"ALK4:actriib heteromultimers and uses thereof" was invented by Ravindra Kumar (Cambridge, Mass.), Asya Grinberg (Cambridge, Mass.), Dianne Sako (Cambridge, Mass.), Robert Scott Pearsall (Cambridge, Mass.) and Roselyne Castonguay (Cambridge, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "In certain aspects, the disclosure provides soluble heteromeric polypeptide complexes comprising an extracellular domain of an ALK4 receptor and an extracellular domain of ActRIIB. In certain aspects, such soluble ALK4:ActRIIB complexes may be used to regulate (promote or inhib...