ALEXANDRIA, Va., Feb. 11 -- United States Patent no. 12,545,736, issued on Feb. 10, was assigned to Acceleron Pharma Inc (Rahway, N.J.).
"ActRII-binding proteins and uses thereof" was invented by Ravindra Kumar (Acton, Mass.), Jonathan Belk (Lebanon, N.H.), Asya Grinberg (Lexington, Mass.), Dianne Sako (Medford, Mass.) and Roselyne Castonguay (Watertown, Mass.).
According to the abstract* released by the U.S. Patent & Trademark Office: "This disclosure provides ActRII-binding proteins such as anti-ActRIIA and anti-ActRIIB antibodies, and compositions and methods for making the ActRII-binding proteins. In certain embodiments, the ActRII-binding proteins inhibit, or antagonize ActRII activity. In addition, the disclosure provides compositio...