ALEXANDRIA, Va., March 26 -- United States Patent no. 12,258,318, issued on March 25, was assigned to ACCELA CHEMBIO Co. LTD. (Shanghai).
"Synthesis method for 1-methyl-1H-indazole-6-carboxylic acid" was invented by Jun Yang (Shanghai), Duoqing Xue (Shanghai), Yong Wu (Shanghai), Lihuang Chen (Shanghai) and Lianhua Zhai (Shanghai).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present application provides a synthesis method for 1-methyl-1H-indazole-6-carboxylic acid. The synthesis method comprises: using 2-fluoro-4-bromobenzaldehyde and methylhydrazine as raw materials to obtain 6-bromo-1-methylindazole by means of an annulation reaction, and then performing a methyl formate reaction and a hydrolysis reac...