ALEXANDRIA, Va., Nov. 11 -- United States Patent no. 12,466,783, issued on Nov. 11, was assigned to ACADIA Pharmaceuticals Inc. (San Diego).

"Neuro-attenuating ketamine and norketamine compounds, derivatives thereof, and methods" was invented by Alex Nivorozhkin (West Roxbury, Mass.) and Nelson Landrau (Marlborough, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention is directed to novel neuro-attenuating norketamine (NANKET) compounds according to any one of formulas (I-shown below), (I-A) and (I-B), or any of the compounds described in Tables A-D, or in any of the Examples provided herein, and pharmaceutically acceptable salts thereof, novel pharmaceutical formulations and novel meth...