US Patent Issued to ACADEMISCH ZIEKENHUIS LEIDEN H.O.D.N. LUMC on Nov. 25 for "Inhibition of polyomavirus replication" (Dutch Inventors)

ALEXANDRIA, Va., Nov. 25 -- United States Patent no. 12,480,122, issued on Nov. 25, was assigned to ACADEMISCH ZIEKENHUIS LEIDEN H.O.D.N. LUMC (Leiden, Netherlands).

"Inhibition of polyomavirus replication" was invented by Eric Peter Van Der Veer (The Hague, Netherlands), Anton Jan Van Zonneveld (Soest, Netherlands) and Jurrien Prins (The Hague, Netherlands).

According to the abstract* released by the U.S. Patent & Trademark Office: "The invention relates to antisense molecules and methods for modulating splicing of polyomavirus T antigen pre-mRNA. In one aspect the invention relates to an antisense oligonucleotide 12 to 30, preferably 17, 18, 19 or 20 to 30 nucleobases in length which comprises a sequence that is the reverse complement o...