US Patent Issued to Academia Sinica on Aug. 12 for "Sialidase-resistant saccharide and method of making and using the same" (American, Taiwanese Inventors)

ALEXANDRIA, Va., Aug. 12 -- United States Patent no. 12,384,811, issued on Aug. 12, was assigned to Academia Sinica (Taipei, Taiwan).

"Sialidase-resistant saccharide and method of making and using the same" was invented by Chi-Huey Wong (Rancho Santa Fe, Calif.) and Hong-Jay Lo (New Taipei, Taiwan).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed are a method of preparing a saccharide that contains a 3-fluoro-sialic acid and a method of bonding it to a homogeneous antibody. Also within the scope of this invention are compounds each containing a 3-fluoro-sialic acid, monoclonal antibodies bonded to Alpha2,6-linked 3-fluoro-sialo-side terminated N-glycans, and treatment of cancer with such monoclonal an...