US Patent Issued to Ablynx on Jan. 13 for "Method for the production of immunoglobulin single variable domains" (Belgian, Austrian Inventors)

ALEXANDRIA, Va., Jan. 13 -- United States Patent no. 12,522,652, issued on Jan. 13, was assigned to Ablynx N.V. (Ghent-Zwijnaarde, Belgium).

"Method for the production of immunoglobulin single variable domains" was invented by Ann Brige (Ertvelde, Belgium), Bart Walcarius (Gentbrugge, Belgium), Yves Meyvis (Ghent, Belgium) and Mauro Sergi (Kufstein, Austria).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to an improved method for the manufacture of immunoglobulin single variable domains. More specifically, the present invention relates to a method of producing immunoglobulin single variable domains in which the proportion of carbamylated variants is strongly reduced or absent and...